2. Anti-infection
  3. Fungal
  4. Stictic acid

Stictic acid 是一种次级代谢产物，可以从地衣 Lobaria pulmonaria (L.) Hoffm 中分离出来。Stictic acid 抑制人结肠腺癌 HT-29 细胞的生长 (IC50: 29.29 μg/mL)。

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Stictic acid

Stictic acid Chemical Structure

CAS No. : 549-06-4

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规格 价格 是否有货 数量
500 μg ￥3240
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Stictic acid 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Stictic acid is a secondary metabolite that can be isolated from the lichen Lobaria pulmonaria (L.) Hoffm. Stictic acid inhibits growth of human colon adenocarcinoma HT-29 cells (IC50: 29.29 μg/mL)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: 1
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
[PMID: 24725159]
HeLa IC50
> 10 μM
Compound: 1
Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
[PMID: 24725159]
Hepatocyte IC50
≤ 13 μM
Compound: 3
Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
[PMID: 33290062]
HL-60 IC50
> 10 μM
Compound: 1
Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
[PMID: 24725159]
HL-60 IC50
> 10 μM
Compound: 1
Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
[PMID: 24725159]
Vero IC50
> 150 μM
Compound: 1
Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
[PMID: 24725159]
Vero IC50
> 150 μM
Compound: 1
Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
[PMID: 24725159]
分子量

386.31

Formula

C19H14O9
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源

Lobaria pulmonaria
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 11 mg/mL (28.47 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.5886 mL 12.9430 mL 25.8859 mL
5 mM 0.5177 mL 2.5886 mL 5.1772 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 98.5%

COA (203 KB)

产品使用指南 (1538 KB)
参考文献

Stictic acid 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5886 mL 12.9430 mL 25.8859 mL 64.7149 mL
5 mM 0.5177 mL 2.5886 mL 5.1772 mL 12.9430 mL
10 mM 0.2589 mL 1.2943 mL 2.5886 mL 6.4715 mL
15 mM 0.1726 mL 0.8629 mL 1.7257 mL 4.3143 mL
20 mM 0.1294 mL 0.6471 mL 1.2943 mL 3.2357 mL
25 mM 0.1035 mL 0.5177 mL 1.0354 mL 2.5886 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Stictic acid549-06-4Fungalcolon adenocarcinoma,cancerInhibitorinhibitorinhibit

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目录号：
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