1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. Tyrosinase-IN-44

Tyrosinase-IN-44 (Compound 3) 是一种 Tyrosinase 抑制剂,其对单酚酶和二酚酶的 IC50 分别为 0.47 μM 和 0.53 μM。Tyrosinase-IN-44 具有优异的谷胱甘肽过氧化物酶样催化活性和 DPPH 自由基清除活性。Tyrosinase-IN-44 在香蕉汁和苹果汁中具有强大的抗褐变活性,并且通过直接抑制多酚氧化酶 (PPO) 并提供抗氧化活性。Tyrosinase-IN-44 可用于氧化还原调节和食品保鲜。

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Tyrosinase-IN-44

Tyrosinase-IN-44 Chemical Structure

CAS No. : 10200-72-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tyrosinase-IN-44 (Compound 3) is a Tyrosinase inhibitor with IC50s of 0.47  and 0.53 μM for monophenolase and diphenolase, respectively. Tyrosinase-IN-44 has superior glutathione peroxidase-like catalytic and DPPH radical scavenging activity. Tyrosinase-IN-44 has potent antibrowning activity in banana and apple juices by directly inhibiting polyphenol oxidase (PPO) and offering antioxidant activity. Tyrosinase-IN-44 can be used for redox regulation and food preservation[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 GI50
> 50 μM
Compound: 1b
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 27487570]
PC-3 GI50
> 50 μM
Compound: 1b
Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 27487570]
分子量

214.15

Formula

C7H5NSSe

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Tyrosinase-IN-44 相关分类

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  • 稀释计算器

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tyrosinase-IN-44
目录号:
HY-178055
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