2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. VHR-IN-9

VHR-IN-9 是一种选择性痘苗病毒 H1 相关 (VHR) 磷酸酶抑制剂，其 IC50 值为 270 nM。VHR-IN-9 对 MKP-1 (IC50 = 2.8 μM)、CD45 (IC50 = 1.8 μM)、Cdc25A (IC50 = > 10 μM)、PTP1B (IC50 = 2.2 μM) 和 HePTP (IC50 = 2.4 μM) 的抑制活性较弱。VHR-IN-9 可抑制 HeLa 细胞的增殖。VHR-IN-9 可用于宫颈癌的研究。

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VHR-IN-9

VHR-IN-9 Chemical Structure

CAS No. : 1146616-18-3

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VHR-IN-9 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VHR-IN-9 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 270 nM. VHR-IN-9 shows very weaker inhibitory activity against MKP-1 (IC50 = 2.8 μM), CD45 (IC50 = 1.8 μM), Cdc25A (IC50 = > 10 μM), PTP1B (IC50 = 2.2 μM), and HePTP (IC50 = 2.4 μM). VHR-IN-9 inhibits the proliferation of HeLa cells. VHR-IN-9 can be used for the research of cervical cancer[1].

体外研究
(In Vitro)

VHR-IN-9 (Compound SA5) (20 μM, 24 h) 抑制 HeLa 细胞的增殖，并且对正常人角质形成细胞 (NK 细胞)的存活和增殖没有明显的毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

VHR-IN-9 相关抗体:
分子量

618.77

Formula

C26H26N4O6S4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VHR-IN-9 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VHR-IN-91146616-18-3PhosphataseVHR phosphatasemultidentate inhibitorscervical cancerstructure-based drug designselectivityInhibitorinhibitorinhibit

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