2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Cannabinoid Receptor Endogenous Metabolite
  4. 2-Arachidonoylglycerol

2-Arachidonoylglycerol  (Synonyms: 2-花生酰基甘油)

目录号: HY-W011051 纯度: 99.92%
COA 产品使用指南 技术支持

2-Arachidonoylglycerol 是中枢神经系统中的一种内源性大麻素配体。

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2-Arachidonoylglycerol

2-Arachidonoylglycerol Chemical Structure

CAS No. : 53847-30-6

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规格 价格 是否有货 数量
1 mg (26.4 mM * 100 μL in Acetonitrile) ￥1500
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Other Forms of 2-Arachidonoylglycerol:

2-Arachidonoylglycerol 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 Cannabinoid Receptor 亚型特异性产品:

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CB1 CB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HL-60 EC50
17 nM
Compound: 1, 2-AG
Agonist activity at CB2 receptor expressed in HL60 cells assessed as increase in intracellular free calcium concentrations
Agonist activity at CB2 receptor expressed in HL60 cells assessed as increase in intracellular free calcium concentrations
[PMID: 17110113]
NG108-15 EC50
23 nM
Compound: 1, 2-AG
Agonist activity at CB1 receptor expressed in NG108-15 cells assessed as increase in intracellular free calcium concentrations
Agonist activity at CB1 receptor expressed in NG108-15 cells assessed as increase in intracellular free calcium concentrations
[PMID: 17110113]
体外研究
(In Vitro)

2-Arachidonoylglycerol 是一种从肠道组织中分离的大麻素配体。2-Arachidonoylglycerol 作为完全激动剂激活神经元大麻素受体，并阻止 CA3-CA1 突触处诱导长期增强。2-Arachidonoylglycerol 与大麻素受体结合，并发挥多种典型的大麻素药物作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2-Arachidonoylglycerol 相关抗体:
分子量

378.55

Formula

C23H38O4
CAS 号
性状

液体

颜色

Colorless to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: 99.92%

COA (287 KB) RP-HPLC (237 KB)

产品使用指南 (1538 KB)
参考文献

2-Arachidonoylglycerol 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Arachidonoylglycerol53847-30-6Cannabinoid ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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目录号：
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