2. Anti-infection
  3. Bacterial
  4. 22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin 

目录号: HY-146756
产品使用指南 技术支持

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin (compound 6n) 是一种抗细菌 (antibacterial) 的 pleuromutilin 衍生物，对 Gram-positive pathogens (GPPs) 和 Mycoplasma pneumoniae 具有抗菌效果。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin Chemical Structure

CAS No. : 2780409-77-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin (compound 6n) is an antibacterial pleuromutilin derivative against Gram-positive pathogens (GPPs) and Mycoplasma pneumoniae[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HGC-27 IC50
> 10 μM
Compound: 6n
Cytotoxicity against human HGC-27 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human HGC-27 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 35220163]
HT-29 IC50
> 10 μM
Compound: 6n
Cytotoxicity against human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 35220163]
HepG2 IC50
> 10 μM
Compound: 6n
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 35220163]
MCF7 IC50
> 10 μM
Compound: 6n
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 35220163]
U-87MG ATCC IC50
> 10 μM
Compound: 6n
Cytotoxicity against human U87 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human U87 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 35220163]
体外研究
(In Vitro)

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin (compound 6n) (0.0625 -128 µg/mL, 8 h) shows antibacterial activity with MICs of 0.0625, 0.5, 8, 0.125, 0.0625, and 0.5 µg/mL against MSSA, MRSA, E.faecium, M.pneumonia (ATCC15331), M.pneumonia (ATCC29342), and M.pneumonia (resistant strain, clinically isolated strain), respectively[1].
22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin (0-10 µg/mL, 72 h) shows low cytotoxicity in human cancer cells[1].
22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin exhibits good ADMET properties with high LogS, attractive ALogP, low PPB, non-Ames toxic, and non-carcinogenic[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: Five human cancer cell lines (HeG2, U87, HGC27, HT29 and MCF2)
Concentration: 0-10 µg/mL
Incubation Time: 72 h
Result: Showed low cytotoxicity ((IC50>10 μmol/L).
分子量

526.66

Formula

C30H42N2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin2780409-77-8BacterialGram-positiveMycoplasma pneumoniaeStaphylococcus aureusStaphylococcus epidermidis Enterococcus faeciumHeG2U87HGC27HT29MCF2Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin
目录号：
HY-146756
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z