2. Anti-infection
  3. Fungal
  4. 3',5,5'-Trichlorosalicylanilide

3',5,5'-Trichlorosalicylanilide  (Synonyms: TCSA)

目录号: HY-W706466
产品使用指南 技术支持

3',5,5'-Trichlorosalicylanilide (TCSA) 可作为真菌形态发生的抑制剂，防止生物膜形成并阻碍宿主细胞入侵。

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3',5,5'-Trichlorosalicylanilide

3',5,5'-Trichlorosalicylanilide Chemical Structure

CAS No. : 106480-60-8

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规格 价格 是否有货 数量
100 mg ￥960
4 - 5 周
1 g ￥2886
4 - 5 周
10 g 询价 4 - 5 周
50 g   询价  

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Customer Review

3',5,5'-Trichlorosalicylanilide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

3',5,5'-Trichlorosalicylanilide (TCSA) acts as an inhibitor of fungal morphogenesis, preventing biofilm formation and hindering host cell invasion.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 IC50
0.7 μM
Compound: 18
Inhibition of Wnt/beta-catenin in HEK293 cells assessed as inhibition of Wnt3A-stimulated TOPFlash activity after 8 hrs
Inhibition of Wnt/beta-catenin in HEK293 cells assessed as inhibition of Wnt3A-stimulated TOPFlash activity after 8 hrs
[PMID: 26272032]
J774.A1 CC50
38.75 μM
Compound: 27
Cytotoxicity against mouse J774A.1 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse J774A.1 cells assessed as reduction in cell viability by MTT assay
[PMID: 36565533]
Macrophage IC50
3.1 μM
Compound: 76
Cytotoxicity against mouse macrophage cell line J774.1 (ATCC TIB-67) for 3 days by Alamar Blue
Cytotoxicity against mouse macrophage cell line J774.1 (ATCC TIB-67) for 3 days by Alamar Blue
[PMID: 23211970]
Platelet IC50
3.03 μM
Compound: 39
Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubated for 30 mins before collagen stimulation by aggregometry
Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of collagen-induced platelet aggregation pre-incubated for 30 mins before collagen stimulation by aggregometry
[PMID: 32345019]
Platelet IC50
> 10 μM
Compound: 39
Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of TRAP6-induced platelet aggregation pre-incubated for 30 mins before TRAP6 stimulation by aggregometry
Antagonist activity P2X1 receptor in Apyrase pre-treated human platelets assessed as inhibition of TRAP6-induced platelet aggregation pre-incubated for 30 mins before TRAP6 stimulation by aggregometry
[PMID: 32345019]
Platelet IC50
> 20 μM
Compound: 39
Antagonist activity P2X1 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation pre-incubated for 30 mins before ADP stimulation by aggregometry
Antagonist activity P2X1 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation pre-incubated for 30 mins before ADP stimulation by aggregometry
[PMID: 32345019]
Vero CC50
6.49 μM
Compound: 27
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability by MTT assay
[PMID: 36565533]
分子量

316.57

Formula

C13H8Cl3NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

3',5,5'-Trichlorosalicylanilide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3',5,5'-Trichlorosalicylanilide106480-60-8TCSAFungalInhibitorinhibitorinhibit

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