2. Metabolic Enzyme/Protease
  3. Acyltransferase
  4. 447C88

447C88 是一种酰基辅酶 A 胆固醇酰基转移酶 (ACAT) 抑制剂，IC50 为 23 nM。447C88 能够降低血浆胆固醇水平。447C88 可用于高脂血症等内分泌与代谢疾病的研究。

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447C88

447C88 Chemical Structure

CAS No. : 130400-16-7

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447C88 相关抗体

Top Publications Citing Use of Products

查看 Acyltransferase 亚型特异性产品:

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ACAT1 ACAT2 MGAT2 ACAT

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

447C88 is an acyl-coenzyme A cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 23 nM. 447C88 can reduce plasma cholesterol levels and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia[1][2].

IC50 & Target[2]

ACAT

23 nM (IC50)

分子量

444.60

Formula

C27H38F2N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

447C88 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

447C88130400-16-7AcyltransferaseDiacylglycerol acyltransferaseDiglyceride acyltransferaseacyl-CoA:cholesterol acyltransferasemono- acylglycerol acyltransferaseACAThyperlipidemiaInhibitorinhibitorinhibit

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产品名称：
447C88
目录号：
HY-19112
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