1. GPCR/G Protein
  2. Oxytocin Receptor
  3. Retosiban

Retosiban (Synonyms: GSK 221149; GSK 221149A)

目录号: HY-14778
产品使用指南

Retosiban (GSK221149A) 是有效,选择性的催产素 (oxytocin) 拮抗剂, Ki值为0.65 nM。

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Retosiban Chemical Structure

Retosiban Chemical Structure

CAS No. : 820957-38-8

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Description

Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM.

IC50 & Target

IC50: 0.65 nM (Oxytocin)[1]

Clinical Trial
Molecular Weight

494.58

Formula

C₂₇H₃₄N₄O₅

CAS No.

820957-38-8

SMILES

O=C([C@@H](C1CC2=C(C=CC=C2)C1)N3)N([C@H](C4=COC(C)=N4)C(N5CCOCC5)=O)[C@H]([C@H](CC)C)C3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

RetosibanGSK 221149 GSK 221149AGSK221149GSK-221149Oxytocin ReceptorOXTRInhibitorinhibitorinhibit

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产品名称:
Retosiban
目录号:
HY-14778
需求量: