1. Immunology/Inflammation Epigenetics Metabolic Enzyme/Protease
  2. COX Histone Acetyltransferase Endogenous Metabolite
  3. Acetaminophen-d3

Acetaminophen-d3  (Synonyms: 对乙酰氨基酚-d3; Paracetamol-d3; 4-Acetamidophenol-d3; 4'-Hydroxyacetanilide-d3)

目录号: HY-66005S1 纯度: ≥99.0%
COA 产品使用指南

Acetaminophen-d3 是 Acetaminophen 的氘代物。Acetaminophen (Paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂,IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。Acetaminophen 是广泛使用的解热和止痛剂。

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Acetaminophen-d<sub>3</sub> Chemical Structure

Acetaminophen-d3 Chemical Structure

CAS No. : 60902-28-5

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生物活性

Acetaminophen-d3 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

154.18

Formula

C8H6D3NO2

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

对乙酰氨基酚-d3;乙酰氨基酚-d3;扑热息痛-d3;退热净-d3;醋氨酚-d3;对醋氨酚-d3;索密痛-d3;乙酰氨基苯酚-d3;二醋洛尔-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Acetaminophen-d3
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HY-66005S1
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