2. Protein Tyrosine Kinase/RTK
  3. Insulin Receptor
  4. Acetyl Gastric Inhibitory Peptide (human)

Acetyl Gastric Inhibitory Peptide (human)  (Synonyms: Human N-acetyl GIP)

目录号: HY-P3580
产品使用指南

摩尔计算器

Acetyl Gastric Inhibitory Peptide (human) 是葡萄糖依赖性的胰岛素性多肽的脂肪酸衍生类似物，具有改善的抗高血糖和胰岛素性。Acetyl Gastric Inhibitory Peptide (human) 可用于糖尿病、胰岛素抵抗和肥胖的研究。

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Custom Peptide Synthesis

Acetyl Gastric Inhibitory Peptide (human) Chemical Structure

Acetyl Gastric Inhibitory Peptide (human) Chemical Structure

CAS No. : 299898-33-2

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规格 是否有货
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250 mg   询价  

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Acetyl Gastric Inhibitory Peptide (human) 的其他形式现货产品:

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Other Forms of Acetyl Gastric Inhibitory Peptide (human):

Acetyl Gastric Inhibitory Peptide (human) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity[1][2][3].

体外研究
(In Vitro)

Acetyl Gastric Inhibitory Peptide (human) 在转染人 GIP 受体的中国仓鼠肺成纤维细胞中诱导环腺苷 3'5' 单磷酸 (cAMP) 产生，EC50 值为 1.9 nM[1]。
与天然 GIP 相比，Acetyl Gastric Inhibitory Peptide (human) (10-13-10-8 nM) 在刺激胰岛素释放方面表现出强大的作用[1]。
Acetyl Gastric Inhibitory Peptide (human) 可改善葡萄糖不耐受、2 型糖尿病、β 细胞葡萄糖不敏感、胰岛素抵抗和胰岛素分泌减少[2]。
Acetyl Gastric Inhibitory Peptide (human) 具有两种脂肪酸衍生的 N 末端乙酰化 GIP 类似物的代谢稳定性以及降血糖和胰岛素调节活性，并已在体外和体内进行了评估[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Acetyl Gastric Inhibitory Peptide (human) 相关抗体:
体内研究
(In Vivo)

Acetyl Gastric Inhibitory Peptide (human) (25 nmol/kg；腹腔注射；单剂量) 显示出对血浆二肽基肽酶 IV 降解的抵抗力，从而增强生物活性并改善体内抗糖尿病潜力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Obese hyperglycaemic (ob/ob) mice[1]
Dosage: 25 nmol/kg
Administration: Intraperitoneal injection; single dose
Result: Lowered individual glucose values at 60 min together with the areas under the curve for glucose compared to native GIP.
分子量

5025.60

Formula

C228H340N60O67S
CAS 号
Sequence

Ac-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln
Sequence Shortening

Ac-YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Acetyl Gastric Inhibitory Peptide (human) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetyl Gastric Inhibitory Peptide (human)299898-33-2Human N-acetyl GIPInsulin Receptorpeptide analogdiabetesinsulinresistanceobesitygastric insulin peptide analogdipeptidyl peptidase degradation resistancehypoglycemic GIP analoginsulin modulatorInhibitorinhibitorinhibit

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