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  3. Acetyl tetrapeptide-2

Acetyl tetrapeptide-2 是一种具有抗衰老活性的生物活性肽。Acetyl tetrapeptide-2 可以减少胸腺因子的流失。Acetyl tetrapeptide-2 可以增加 HaCaT 细胞的硬度。Acetyl tetrapeptide-2 可以刺激包括胶原蛋白和弹性蛋白在内的皮肤结构元素。

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Custom Peptide Synthesis

Acetyl tetrapeptide-2

Acetyl tetrapeptide-2 Chemical Structure

CAS No. : 757942-88-4

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50 mg ¥500
In-stock
100 mg ¥700
In-stock
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500 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Acetyl tetrapeptide-2 is a bio-active peptide that exhibits anti-aging activity. Acetyl tetrapeptide-2 can reduce loss of thymic factors. Acetyl tetrapeptide-2 can increase the stiffness of HaCaT cells. Acetyl tetrapeptide-2 is a stimulator of structural skin elements including collagen and elastin[1][2][3].

体外研究
(In Vitro)

Acetyl tetrapeptide-2 (Compound P1) (0.5-50 μg/mL,48 小时) 导致 HaCaT 细胞硬度增加[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence[3]

Cell Line: HaCaT cells
Concentration: 0.5, 5, 50 μg/mL
Incubation Time: 48 h
Result: Contributed to cellular cohesion due to Focal Adhesions (FAs), interface between the actin cytoskeleton and extracellular matrix by overexpression genes involved in these processes.
Resulted in increased production of elastin, and collagen type I.
Showed similar high density of actin filaments in the whole cytoplasm area, even in peripheral parts.

Real Time qPCR[3]

Cell Line: HaCaT cells
Concentration: 0.5, 5, 50 μg/mL
Incubation Time: 48 h
Result: Significantly decreased the relative mRNA expression of ACTN1, ITGB4, and COL17A1 with 50 μg/mL, whilst significantly upregulated COL17A1 with 0.5 μg/mL.
分子量

565.62

Formula

C26H39N5O9

CAS 号
性状

固体

颜色

White to off-white

Sequence

Ac-Lys-Asp-Val-Tyr

Sequence Shortening

Ac-KDVY

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 100 mg/mL (176.80 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7680 mL 8.8399 mL 17.6797 mL
5 mM 0.3536 mL 1.7680 mL 3.5359 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7680 mL 8.8399 mL 17.6797 mL 44.1993 mL
5 mM 0.3536 mL 1.7680 mL 3.5359 mL 8.8399 mL
10 mM 0.1768 mL 0.8840 mL 1.7680 mL 4.4199 mL
15 mM 0.1179 mL 0.5893 mL 1.1786 mL 2.9466 mL
20 mM 0.0884 mL 0.4420 mL 0.8840 mL 2.2100 mL
25 mM 0.0707 mL 0.3536 mL 0.7072 mL 1.7680 mL
30 mM 0.0589 mL 0.2947 mL 0.5893 mL 1.4733 mL
40 mM 0.0442 mL 0.2210 mL 0.4420 mL 1.1050 mL
50 mM 0.0354 mL 0.1768 mL 0.3536 mL 0.8840 mL
60 mM 0.0295 mL 0.1473 mL 0.2947 mL 0.7367 mL
80 mM 0.0221 mL 0.1105 mL 0.2210 mL 0.5525 mL
100 mM 0.0177 mL 0.0884 mL 0.1768 mL 0.4420 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Acetyl tetrapeptide-2
目录号:
HY-P2663
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