1. PROTAC
  2. PROTAC Linker
  3. Acid-PEG3-C2-Boc

Acid-PEG3-C2-Boc 

目录号: HY-130549
产品使用指南

Acid-PEG3-C2-Boc是一种 PROTAC linker,属于 PEGAlkyl/ether 类,可以用于合成降解 EGFR 和抑制 mTOR 的 PROTAC。

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Acid-PEG3-C2-Boc Chemical Structure

Acid-PEG3-C2-Boc Chemical Structure

CAS No. : 1807539-06-5

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Description

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR[1][2].

IC50 & Target

PEGs

 

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

306.35

Formula

C₁₄H₂₆O₇

CAS No.

1807539-06-5

SMILES

CC(C)(C)OC(CCOCCOCCOCCC(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Acid-PEG3-C2-BocPROTAC LinkerPROTAClinkermTOREGFRInhibitorinhibitorinhibit

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产品名称:
Acid-PEG3-C2-Boc
目录号:
HY-130549
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