2. Metabolic Enzyme/Protease Apoptosis
  3. Necroptosis Aldehyde Dehydrogenase (ALDH)
  4. ALDH1A inhibitor 673A

ALDH1A inhibitor 673A  (Synonyms: ALDH1Ai 673A)

目录号: HY-122912
产品使用指南

摩尔计算器

ALDH1A inhibitor 673A 是一种 ALDH1A 抑制剂。ALDH1A inhibitor 673A 抑制所有三个 ALDH1A 家族成员 (对 ALDH1A1、ALDH1A2、ALDH1A3 的 IC50 分别为 246 nM、230 nM、348 nM)。ALDH1A inhibitor 673A 诱导 CD133+ 卵巢 CSC 细胞坏死。ALDH1A inhibitor 673A 还可以抑制化疗耐药肿瘤的生长。

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ALDH1A inhibitor 673A Chemical Structure

ALDH1A inhibitor 673A Chemical Structure

CAS No. : 109437-62-9

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ALDH1A inhibitor 673A 相关抗体

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查看 Aldehyde Dehydrogenase (ALDH) 亚型特异性产品:

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ALDH1 ALDH2 ALDH3

  • 生物活性

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  • 参考文献

生物活性

ALDH1A inhibitor 673A is an ALDH1A inhibitor. ALDH1A inhibitor 673A inhibits all three ALDH1A family members (IC50: 246 nM, 230 nM, 348 nM for ALDH1A1, ALDH1A2, ALDH1A3 respectively. ALDH1A inhibitor 673A induces necroptotic cell death preferentially in CD133+ ovarian CSCs. ALDH1A inhibitor 673A also inhibits chemotherapy-resistant tumor growth[1].

分子量

223.27

Formula

C15H13NO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ALDH1A inhibitor 673A 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

ALDH1A inhibitor 673A109437-62-9ALDH1Ai 673ANecroptosisAldehyde Dehydrogenase (ALDH)Ovarian cancertumorstem-like cellschemotherapy-resistantInhibitorinhibitorinhibit

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