2. Immunology/Inflammation Apoptosis
  3. CD20 Apoptosis
  4. Anti-CD20 Antibody (mAb 1.5.3)

Anti-CD20 Antibody (mAb 1.5.3) 

目录号: HY-P991547
技术支持

Anti-CD20 Antibody (mAb 1.5.3) 是一种全人源 IgG1 抗 CD20 抗体。Anti-CD20 Antibody (mAb 1.5.3) 在体外可增强促细胞凋亡 (apoptosis) 活性。Anti-CD20 Antibody (mAb 1.5.3) 介导补体依赖性细胞毒作用和抗体依赖性细胞毒作用。Anti-CD20 Antibody (mAb 1.5.3) 在各种肿瘤异种移植模型中均表现出增强的抗肿瘤活性。Anti-CD20 Antibody (mAb 1.5.3) 在灵长类动物药效动力学模型中，在淋巴结器官和骨髓中产生了优异的B细胞耗竭特性。Anti-CD20 Antibody (mAb 1.5.3) 可用于 B 细胞恶性肿瘤的研究。

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Anti-CD20 Antibody (mAb 1.5.3)

Anti-CD20 Antibody (mAb 1.5.3) Chemical Structure

CAS No. : 922534-56-3

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Anti-CD20 Antibody (mAb 1.5.3) 相关抗体

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  • 生物活性

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生物活性

Anti-CD20 Antibody (mAb 1.5.3) is a fully human IgG1 anti-CD20 antibody. Anti-CD20 Antibody (mAb 1.5.3) evokes enhanced pro-apoptotic activity in vitro. Anti-CD20 Antibody (mAb 1.5.3) mediated both complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Anti-CD20 Antibody (mAb 1.5.3) demonstrates enhanced anti-tumor activity in various tumor xenograft models. Anti-CD20 Antibody (mAb 1.5.3) produces a superior B-cell depletion profile in lymph node organs and bone marrow in a primate pharmacodynamic model. Anti-CD20 Antibody (mAb 1.5.3) can be studied in research for B-cell maglignancies[1].

反应种属

Human
IC50 & Target

CD20/MS4A1
基因 ID

931  [NCBI]

Accession
靶点

CD20/MS4A1
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-CD20 Antibody (mAb 1.5.3) 相关分类

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Keywords:

Anti-CD20 Antibody (mAb 1.5.3)922534-56-3CD20ApoptosisInhibitorinhibitorinhibit

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