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Anti-virus agent 1 

目录号: HY-131233
产品使用指南

Anti-virus agent 1 (compound 4i) 是 GS-5734 (HY-104077; Remdesivir) 的氨基磷酸酯前药,具有有效的抗病毒 (antiviral) 活性。Anti-virus agent 1 用于冠状病毒和埃博拉病毒 (EBOV) 的研究。

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Anti-virus agent 1 Chemical Structure

Anti-virus agent 1 Chemical Structure

CAS No. : 1911578-83-0

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Description

Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV)[1][2].

In Vitro

Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC50=1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC50=367 nM), human macrophages (EC50=297 nM). Anti-virus agent 1 has a CC50 of 21 μM in MT4 cell (human leukemia T-cell)[1].

Molecular Weight

560.50

Formula

C₂₄H₂₉N₆O₈P

CAS No.

1911578-83-0

SMILES

N#C[C@@]([C@@H]([C@@H]1O)O)(C2=CC=C3N2N=CN=C3N)O[C@@H]1CO[P@](OC4=CC=CC=C4)(N[C@@H](C)C(OC(C)C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Anti-virus agent 1OthersGS-5734antiviralcoronavirusEbolavirusEBOVRemdesivirInhibitorinhibitorinhibit

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产品名称:
Anti-virus agent 1
目录号:
HY-131233
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