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  5. HLA-DQA1 抗体 (YA2433)

HLA-DQA1 抗体 (YA2433)

目录号: HY-P82688
抗体使用指南 技术支持

HLA-DQA1 Antibody (YA2433) 是一个兔来源、无偶联标记、抗 HLA-DQA1 的 IgG 单克隆抗体。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 μL ￥470 1 - 2 周
50 μL ￥1220 1 - 2 周
100 μL ￥2000 1 - 2 周
250 μL   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

HLA-DQA1 Antibody (YA2433) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DQA1.
研究背景

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
基因 ID
蛋白数据库
中文名
HLA-DQA1 抗体 (YA2433)
同用名
HLA-DQA1; CD; CELIAC1; DQ-A1; GSE; HLA-DQA; DQ alpha 1 chain; DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1
分子量

Predicted band size: 28 kDa; Observed band size: 28 kDa
纯度

Affinity Chromatography
偶联

Non-conjugated
修饰

Unmodified
研究领域

Immunology
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Recombinant, Monoclonal
宿主

Rabbit
反应物种

Human, Mouse, Rat
推荐稀释比例

WB: 1:500-1:1000; IHC: 1:50-1:100; IP: 1:50
应用

WB, IHC-P, IP
性状

液体
组分

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
敏感性

Endogenous
免疫原

A synthesized peptide derived from human HLA-DQA1
数据库

Entrez Gene: 100133678 Human ; 100507686 Human ; 100509457 Human ; 3117 Human ;

SwissProt: P01909 Human ;

OMIM: 146880 Human

文件资料
抗体使用指南 (1083 KB)

HLA-DQA1 Antibody (YA2433) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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