T Cell Leukemia/Lymphoma Protein 1A 抗体 (YA1704)

T Cell Leukemia/Lymphoma Protein 1A Antibody (YA1704) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to T Cell Leukemia/Lymphoma Protein 1A.

Overexpression of the TCL1 related gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 related gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

P56279

Predicted band size: 13 kDa; Observed band size: 13 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100

WB, IHC-P, ICC/IF, FC

液体

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human TCL1