Vitronectin 抗体 (YA2402)

Vitronectin Antibody (YA2402) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitronectin.

The protein encoded by The related gene functions in part as an adhesive glycoprotein. Differential expression of The protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. The secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. The protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. The protein can also promote extracellular matrix degradation and thus plays a role in tumorirelated genesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of The protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein.

P04004

Predicted band size: 54 kDa; Observed band size: 70 kDa

Affinity Purified

Non-conjugated

Unmodified

Cardiovascular

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1:500-1:1000; IHC: 1:50-1:100; IF: 1:50-1:200

WB, IHC-F, IHC-P, ICC/IF

液体

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Vitronectin