1. Peptides
  2. Big Gastrin I (human) (TFA)

Big Gastrin I, human (TFA) 是一种胃肠道激素,由 34 个氨基酸组成。可作为研究癌症、自身免疫疾病、纤维化疾病、炎性疾病、神经性疾病或心血管疾病等的潜在物质。

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Big Gastrin I (human) (TFA) Chemical Structure

Big Gastrin I (human) (TFA) Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Big Gastrin I, human (TFA) is a gastrointestinal hormone consisting of 34 amino acids. Big Gastrin I, human (TFA) can be used as a potential substance for the study of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological diseases or cardiovascular diseases[1].

体外研究
(In Vitro)

Big Gastrin I, human (TFA) (10 μg/mL, 6 days) inhibits 11.3% of HBV replication in HepG2 cells containing the hepatitis B virus (HBV) ayw strain genome and maintains cell viability at 88.7%[1].
Big Gastrin I, human (TFA) (10 μg/mL, 24 h) can arrest cells mainly in G0/G1 phase and induces apoptosis in human A549 cells[1].
Big Gastrin I, human (TFA) (10 μg/mL, 22 h) can inhibit 35% of cell migration in human endothelial cells (HUVEC)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis[1]

Cell Line: Human A549 cells
Concentration: 10 μg/mL
Incubation Time: 24 hours
Result: Resulted in 55.9% cells stalled in G0/G1 phase, 34.1% cells stalled in S phase and 10% cells stalled in G2/M phase.

Apoptosis Analysis[1]

Cell Line: Human A549 cells
Concentration: 10 μg/mL
Incubation Time: 24 hours
Result: Induced 1.1% cells apoptosis.
分子量

3963.21

Formula

C178H252F3

Sequence Shortening

{Glp}LGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Big Gastrin I (human) (TFA)
目录号:
HY-P3446A
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