1. PROTAC
  2. PROTAC Linkers
  3. Bis-Mal-PEG11

Bis-Mal-PEG11 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

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Bis-Mal-PEG11 Chemical Structure

Bis-Mal-PEG11 Chemical Structure

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10 mg ¥800
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25 mg ¥1600
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50 mg ¥2500
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bis-Mal-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

846.92

Formula

C38H62N4O17

性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Bis-Mal-PEG11 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bis-Mal-PEG11
目录号:
HY-140995
需求量: