1. Others Protein Tyrosine Kinase/RTK Autophagy
  2. Isotope-Labeled Compounds Src Bcr-Abl Autophagy
  3. Bosutinib-d8

Bosutinib-d8  (Synonyms: SKI-606-d8)

目录号: HY-10158S
COA 产品使用指南

Bosutinib-d8 是 Bosutinib 的氘代物。Bosutinib 是 Src/Abl 的双抑制剂, IC50 分别为 1.2 nM 和 1 nM。

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Bosutinib-d<sub>8</sub> Chemical Structure

Bosutinib-d8 Chemical Structure

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规格 是否有货
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查看 Src 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bosutinib-d8 is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively[1][2].

IC50 & Target

IC50: 1.2 nM (Src), 1 nM (Abl)[1]

分子量

538.50

Formula

C26H21D8Cl2N5O3

性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bosutinib-d8
目录号:
HY-10158S
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