2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. Cannabisin F

Cannabisin F 是一种 SIRT1 调制器。Cannabisin F 作为大麻籽木素酰胺，可用于抗炎、抗氧化研究。Cannabisin F 作为SIRT1/NF-κB 和 Nrf2 的调节因子，可能是一种潜在的神经退行性疾病的调节剂。

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Cannabisin F Chemical Structure

Cannabisin F Chemical Structure

CAS No. : 163136-19-4

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Cannabisin F 相关抗体

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查看 Sirtuin 亚型特异性产品:

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Sirtuin SIRT1 SIRT2 SIRT3 SIRT6 SIRT5 SIRT7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2[1].

IC50 & Target

SIRT1[1]
体外研究
(In Vitro)

Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1[1].
Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cannabisin F 相关抗体:

Cell Viability Assay[1]

Cell Line: BV2 microglia cells
Concentration: 0~15 µM
Incubation Time: 24 hours
Result: Had no significant effect on cell survival.

Western Blot Analysis[1]

Cell Line: BV2 microglia cells
Concentration: 0~15 µM
Incubation Time: 1 hour
Result: Inhibited the phosphorylation of IκBα, p65, but enhanced the expression of Nrf2 and HO-1.
分子量

624.68

Formula

C36H36N2O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cannabisin F 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Cannabisin F163136-19-4Sirtuinhempseedlignanamideanti-inflammatoryanti-oxidativepotentialneurodegenerativeInhibitorinhibitorinhibit

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