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Chlormethiazole hydrochloride (Synonyms: Clomethiazole hydrochloride)

目录号: HY-A0296 纯度: 98.38%
产品使用指南

Clomethiazole hydrochloride 是一种镇静剂和抗惊厥药。Clomethiazole hydrochloride 具有神经保护作用,可抑制 MDMA 诱导的血清素能神经末梢退化。

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Chlormethiazole hydrochloride Chemical Structure

Chlormethiazole hydrochloride Chemical Structure

CAS No. : 6001-74-7

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥715 In-stock
10 mg ¥650 In-stock
50 mg ¥2300 In-stock
100 mg ¥3900 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Clomethiazole hydrochloride is a sedative and anticonvulsant. Clomethiazole hydrochloride is neuroprotective and prevents the degeneration of serotonergic nerve terminals induced by 3,4-methylenedioxymethamphetamine (MDMA)[1][2].

Molecular Weight

198.11

Formula

C₆H₉Cl₂NS

CAS No.

6001-74-7

SMILES

CC1=C(CCCl)SC=N1.Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (630.96 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0477 mL 25.2385 mL 50.4770 mL
5 mM 1.0095 mL 5.0477 mL 10.0954 mL
10 mM 0.5048 mL 2.5239 mL 5.0477 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案,配制前请先配制澄清的储备液,再依次添加助溶剂 (为保证实验结果的可靠性,体内实验的工作
液,建议您现用现配,当天使用;澄清的储备液可以根据储存条件,适当保存;以下溶剂前的百分比是指该溶剂在您配制终溶液中的体积占比):

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (10.50 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (10.50 mM); Clear solution

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (10.50 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Chlormethiazole hydrochloride
目录号:
HY-A0296
需求量:

Chlormethiazole hydrochloride

Cat. No.: HY-A0296