2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Citronellal

Citronellal 是一种单萜，存在于多种芳香植物的精油中，具有抗炎和抗伤害作用。Citronellal 可减轻机械性伤害感受，部分通过 NO-cGMP-ATP 敏感的 K+ 通道通路介导。Citronellal 可诱导自发活动减少、共济失调、镇痛和镇静。Citronellal 可减轻小鼠模型中的机械性伤害感受反应。

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Citronellal

Citronellal Chemical Structure

CAS No. : 106-23-0

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规格 价格 是否有货 数量
100 mg ￥248
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500 mg ￥420
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1 g ￥604
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Other Forms of Citronellal:

Citronellal 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Citronellal is a monoterpene that can be found in the essential oils in various aromatic species of plants, with antiinflammatory and antinociceptive properties. Citronellal attenuates mechanical nociception, mediated in part by the NO-cGMP-ATP-sensitive K+ channel pathway. Citronellal induces reduction of spontaneuous activity, ataxia, analgesia, and sedation in vivo. Citronellal can attenuate mechanical nociception response in mouse model[1][2].

体内研究
(In Vivo)

Citronellal (Compound CTL) (50-200 mg/kg，腹腔注射，单剂量) 对瑞士小鼠的中枢神经系统表现出抑制作用[1]。
Citronellal (200 mg/kg，腹腔注射，单剂量) 显著增加瑞士小鼠模型对热刺激的反应时间和潜伏期[1]。
Citronellal (25-100 mg/kg，腹腔注射，单剂量) 显著降低角叉菜胶 (CG) (HY-125474) 在瑞士小鼠中诱发的机械伤害感受[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss mice (30-35 g, 2-3 months)[1]
Dosage: 50, 100, 200 mg/kg
Administration: Intraperitoneal injection (i.p.)
Result: Decreased spontaneous activity, palpebral ptosis, ataxia, analgesia, and sedation.
Increased sleeping time.
Singnificantly reduced the number of writhing movements in a dose-dependent manner.
Animal Model: Male Swiss mice (28-32 g, 2-3 months)[2]
Dosage: 25, 50, 100 mg/kg
Administration: Intraperitoneal injection (i.p.)
Result: Significantly reduced mechanical nociception induced by TNF-α.
分子量

154.25

Formula

C10H18O
CAS 号
性状

液体（密度：0.8±0.1 g/cm3）

颜色

Colorless to light yellow

中文名称

香茅醛
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
参考文献

Citronellal 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Citronellal106-23-0香茅醛Potassium ChannelKcsAInhibitorinhibitorinhibit

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产品名称：
Citronellal
目录号：
HY-N7126
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