2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. CJ-12255

CJ-12255 是一种选择性 NK1 受体拮抗剂。CJ-12255 对 NK-2 或 NK-3 受体没有亲和力。CJ-12255 可阻断大鼠 P 物质 (SP) 诱导的慢性溃疡性结肠炎 (CUC)。CJ-12255 还可减少大鼠腹部手术期间的腹腔内粘连形成。

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CJ-12255

CJ-12255 Chemical Structure

CAS No. : 146725-78-2

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CJ-12255 相关抗体

Top Publications Citing Use of Products

查看 Neurokinin Receptor 亚型特异性产品:

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NK1R NK2R NK3R

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CJ-12255 is a selective NK1-R antagonist. CJ-12255 has no affinity for the NK-2 or NK-3 receptors. CJ-12255 blocks an substance P (SP)-induced chronic ulcerative colitis (CUC) in rats. CJ-12255 also reduces intraabdominal adhesion formation during abdominal surgery in rats[1][2].

IC50 & Target.
[1]

NK1R

 

分子量

498.66

Formula

C32H38N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CJ-12255 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CJ-12255146725-78-2CJ12255CJ 12255Neurokinin ReceptorNK receptorTachykinin receptorNK1-R Antagonistchronic ulcerative colitisintraabdominal adhesion formationInhibitorinhibitorinhibit

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产品名称：
CJ-12255
目录号：
HY-19182
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