2. Anti-infection
  3. Fungal
  4. CotH3 peptide

CotH3 peptide 是毛霉菌特有的功能肽段，可与宿主 GRP78 受体结合而侵入内皮细胞。CotH3 Peptide 产生的单克隆抗体能保护免疫抑制小鼠免受由德氏根霉 (R. delemar) 和其他毛霉菌引起的毛霉菌病的侵害。CotH3 Peptide 与抗真菌药物协同作用，保护糖尿病酮症酸中毒 (DKA) 小鼠免受德氏根霉感染。

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Custom Peptide Synthesis

CotH3 peptide

CotH3 peptide Chemical Structure

1.  客户无需承担相应的运输费用。

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Customer Review

CotH3 peptide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CotH3 peptide is a functional peptide unique to Mucorales that binds to the host GRP78 receptor and allows them to invade endothelial cells. CotH3 peptide–targeted monoclonal antibodies protect immunosuppressed mice from mucormycosis caused by R. delemar and other Mucorales. CotH3 peptide also synergizes with antifungal drugs to protect mice with diabetic ketoacidosis (DKA) from R. delemar infection[1].

分子量

1768.77

Formula

C69H105N23O30S
Sequence

Met-Gly-Gln-Thr-Asn-Asp-Gly-Ala-Tyr-Arg-Asp-Pro-Thr-Asp-Asn-Asn
Sequence Shortening

MGQTNDGAYRDPTDNN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CotH3 peptide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CotH3 peptideFungalAnti-MucorR. delemarDKA miceInhibitorinhibitorinhibit

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目录号：
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