1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. [DAla4] Substance P (4-11)

[DAla4] Substance P (4-11) 是 Substance P (Substance P (HY-P0201)) 的类似物,可抑制 125I-Bolton Hunter 偶联的 Eledoisin (IC50 为 0.5 μM) 和 125I-Bolton Hunter 偶联的 Substance P (IC50 为 0.15 μM) 与大鼠大脑皮层膜的结合。

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Custom Peptide Synthesis

[DAla4] Substance P (4-11) Chemical Structure

[DAla4] Substance P (4-11) Chemical Structure

CAS No. : 81381-50-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].

体外研究
(In Vitro)

Eledoisin 和 Substance P 是速激肽的一类肽成员,它们具有相似的生物活性谱。[DAla4] Substance P (4-11) ([D-Ala0-(5-11)]SP) 抑制 125I-Bolton Hunter-conjugated 偶联的 Eledoisin 和 125I-Bolton Hunter 偶联的 Substance P 与大鼠大脑皮层膜的结合[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

940.12

Formula

C44H65N11O10S

CAS 号
Sequence Shortening

{D-Ala}-QQFFGLM-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

[DAla4] Substance P (4-11) 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
[DAla4] Substance P (4-11)
目录号:
HY-P3883
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