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  4. Dasiglucagon

Dasiglucagon 是一种人胰高血糖素类似物,可以增加血浆葡萄糖。Dasiglucagon 可用于低血糖症的研究。

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Dasiglucagon Chemical Structure

Dasiglucagon Chemical Structure

CAS No. : 1544300-84-6

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规格 是否有货
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100 mg   询价  
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Dasiglucagon 的其他形式现货产品:

Customer Review

Other Forms of Dasiglucagon:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dasiglucagon is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research[1][2][3].

体内研究
(In Vivo)

Dasiglucagon 的 PK 图谱显示血浆水平的剂量依赖性和快速升高[2]

Dasiglucagon dose
0.1 mg 0.3 mg 0.6 mg 1.0 mg
N 5 16 16 16
AUC0–30min (pmol*h/L) 99.4 (32.0) 302 (78.9) 444 (163) 884 (307)
AUC0–360min (pmol*h/L) 451 (123) 1360 (166) 1630 (368) 4800 (697)
AUC0–inf (pmol*h/L) 451 (123) 1360 (166) 2640 (365) 4810 (696)
Cmax (pmol/L) 334 (113) 976 (208) 1570 (445) 2800 (767)
tmax (h) 0.50 (0.5-0.6) 0.63 (0.3-0.8) 0.58 (0.5-1.7) 0.63 (0.3-0.8)
t1/2 (h) 0.43 (0.07) 0.43 (0.07) 0.49 (0.14) 0.54 (0.17)

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

3381.62

Formula

C152H222N38O50

CAS 号
Sequence

His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-{Aib}-Ala-Arg-Ala-Glu-Glu-Phe-Val-Lys-Trp-Leu-Glu-Ser-Thr

Sequence Shortening

HSQGTFTSDYSKYLD{Aib}ARAEEFVKWLEST

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dasiglucagon
目录号:
HY-P3469
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