2. Cell Cycle/DNA Damage Anti-infection
  3. DNA/RNA Synthesis Bacterial
  4. DNA Gyrase-IN-5

DNA Gyrase-IN-5 (Compound 8I-w) 是一种有效的 DNA gyrase 抑制剂，IC50 值为 0.10 μM。DNA Gyrase-IN-5 对野生型和耐药株均有抗细菌（antibacterial）活性。

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DNA Gyrase-IN-5 Chemical Structure

DNA Gyrase-IN-5 Chemical Structure

CAS No. : 2417016-23-8

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DNA Gyrase-IN-5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains[1].

IC50 & Target

IC50: 0.10 μM (DNA gyrase)[1]
体外研究
(In Vitro)

DNA Gyrase-IN-5 (Compound 8I-w) shows antibacterial activities with IC50 values of 4.7, 7.0, 17.0, 13.5, 1.0, 25.3 and 47.8 μM against E. coli, E. coli E564, E. coli E68, E. coli E48, E. coli E109, Salmonella and S. aureus, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DNA Gyrase-IN-5 相关抗体:
分子量

500.78

Formula

C25H15BrClN5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DNA Gyrase-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNA Gyrase-IN-52417016-23-8DNA/RNA SynthesisBacterialantibacterial activitydrug-resistant bacteriaE. coliSalmonellaS. aureusInhibitorinhibitorinhibit

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