2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. E-2101

E-2101 是一种新型抗痉挛剂。E-2101 是 CYP2C19 和 CYP2D6 的竞争性抑制剂，其 Ki 值分别为 15 μM 和 48 μM。E-2101 经 Cytochromes P450 代谢，生成单羟基化代谢物 (M1 和 M2)、二羟基化代谢物 (M3) 和 N-去烷基化代谢物 (M4)。E-2101 可用于骨骼肌痉挛的研究。

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E-2101

E-2101 Chemical Structure

CAS No. : 265667-22-9

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E-2101 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

E-2101 is a novel antispastic agent. E-2101 is a competitive CYP2C19 and CYP2D6 inhibitor with Ki values of 15 and 48 μM, respectively. E-2101 is metabolized by Cytochromes P450 to form monohydroxylated (M1 and M2), dihydroxylated (M3), and N-dealkylated metabolites (M4). E-2101 can be used in the research of skeletal muscle spasm[1].

IC50 & Target[1]

CYP2C19

15 μM (Ki)

CYP2D6

48 μM (Ki)

分子量

393.50

Formula

C24H28FN3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

E-2101 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E-2101265667-22-9E2101E 2101Cytochrome P450CYPsskeletal muscle spasmantispasticInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-19379
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