1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR
  3. EGFR-IN-71

EGFR-IN-71 

目录号: HY-150781
产品使用指南

EGFR-IN-71 是一种有效的窄谱表皮生长因子受体 (EGFR) 抑制剂,IC50 为 3.7 μM。EGFR-IN-71 可用于脊索瘤的研究。

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EGFR-IN-71 Chemical Structure

EGFR-IN-71 Chemical Structure

CAS No. : 2676155-98-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EGFR-IN-71 is a potent narrow spectrum epidermal growth factor receptor (EGFR) inhibitor with IC50 values of 3.7 μM. EGFR-IN-71 can be used for researching chordoma[1].

IC50 & Target

IC50: 3.7 μM (EGFR)[1]

体外研究
(In Vitro)

EGFR-IN-71 (compound 41) (0-100 μM; 72 h) has inhibitory activity against U-CH1, U-CH2, CH22, UM-Chor1, U-CH12 and U-CH7 chordoma cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U-CH1, U-CH2, CH22, UM-Chor1, U-CH12 and U-CH7
Concentration: 0-100 μM
Incubation Time: 72 h
Result: Exhibited inhibitory activity against U-CH1, U-CH2, CH22, UM-Chor1, U-CH12 and U-CH7 chordoma cell lines with IC50s of 9.1 μM, 16 μM, 0.48 μM, 25 μM, 0.96 μM and 8.0 μM, respectively.
分子量

405.62

Formula

C16H9ClIN3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
EGFR-IN-71
目录号:
HY-150781
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