1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid 

目录号: HY-N3810
产品使用指南

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid 是一种抗黑色素合成的络氨酸酶抑制剂,能够从凤尾蕨中分离得到。ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid 可调节黑色素生成转录因子小眼相关转录因子(MITF)。ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid 的 11α-OH、15-oxo 和 16-en 部分是抑制黑色素合成的关键片段。19-COOH 部分则与抑制 11α-OH KA 及其相关化合物相关的细胞毒性有关。

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ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Chemical Structure

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Chemical Structure

CAS No. : 57719-81-0

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  • 生物活性

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生物活性

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1].

分子量

332.43

Formula

C20H28O4

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid 相关分类

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产品名称:
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
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HY-N3810
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