1. Apoptosis Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Neuronal Signaling
  2. Ferroptosis Apoptosis Mitochondrial Metabolism Calcium Channel
  3. Ferroptosis/apoptosis inducer-3

Ferroptosis/apoptosis inducer-3 

目录号: HY-179016
产品使用指南 技术支持

Ferroptosis/apoptosis inducer-3 (Compound 34) 是一种铁死亡 (Ferroptosis) 和凋亡 (Apoptosis) 诱导剂。Ferroptosis/apoptosis inducer-3 通过引起 G2/M 期细胞周期阻滞、破坏线粒体膜电位、促进脂质过氧化以及通过激活钙/钙调蛋白信号通路增加 Ca2+ 和 Fe2+ 水平,从而诱导铁死亡和凋亡。Ferroptosis/apoptosis inducer-3 对宫颈癌、腺癌、乳腺癌、结肠癌和直肠癌均显示出抗癌作用。

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Ferroptosis/apoptosis inducer-3

Ferroptosis/apoptosis inducer-3 Chemical Structure

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  • 生物活性

  • 参考文献

生物活性

Ferroptosis/apoptosis inducer-3 (Compound 34) is a Ferroptosis and Apoptosis inducer. Ferroptosis/apoptosis inducer-3 induces both Ferroptosis and Apoptosis by causing G2/M phase cell cycle arrest, disrupting mitochondrial membrane potentials, promoting lipid peroxidation, and increasing the levels of Ca2+ and Fe2+ through the activation of calcium/calmodulin signaling. Ferraplasm/apoptosis inducer-3 shows anticancer effects against cervical cancer, adenocarcinoma, breast cancer, colon cancer, and colorectal carcinoma[1].

分子量

419.41

Formula

C22H18FN5O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ferroptosis/apoptosis inducer-3
目录号:
HY-179016
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