2. Inhibitory Antibodies
  3. Frunevetmab

Frunevetmab  (Synonyms: NV-02)

目录号: HY-P99627 纯度: ≥95.0%
COA

摩尔计算器

Frunevetmab (NV-02) 是一种猫源化抗神经生长因子 (NGF) 单克隆抗体，Kd 为 20 pM。Frunevetmab 可有效减轻猫的骨关节炎 (OA) 疼痛。

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Frunevetmab Chemical Structure

Frunevetmab Chemical Structure

CAS No. : 1708936-80-4

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规格 价格 是否有货 数量
1 mg ￥4000
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Frunevetmab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2].

IC50 & Target

Kd: 20 pM (NGF)[2]
体外研究
(In Vitro)

Frunevetmab (NV-02) 以高亲和力和效力中和 NGF，并且不结合补体[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Frunevetmab 相关抗体:
体内研究
(In Vivo)

Frunevetmab (1.0-2.8mg/kg；皮下注射；第 0、28 和 56 天) 对患有自然发生的骨关节炎疼痛和相关的行动障碍和残疾的猫显示出积极的处理效果[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cats with naturally-occurring OA pain and associated mobility impairment and disability[1]
Dosage: 1.0-2.8 mg/kg
Administration: s.c; 3 times at 28-day intervals; on days 0, 28, and 56
Result: Reliefed the pain from osteoarthritis in cats.
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

夫卢维单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Frunevetmab1708936-80-4NV-02夫卢维单抗NV02NV 02OthersanalgesicNGFosteoarthritiscatInhibitorinhibitorinhibit

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