MC1R - melanocortin 1 receptor Gene

中文名称：黑皮质素 1 受体

种属: Rattus norvegicus

关于 MC1R

功能概要

该基因编码的蛋白可启动激素结合活性和黑皮质素受体活性。参与摄食行为的正向调节。预测位于质膜中。该基因的人类直系同源物与家族性黑色素瘤有关；严重抑郁症;黑色素瘤; II型眼皮肤白化病；和色素沉着病。与人类 MC1R（黑皮质素 1 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables hormone binding activity and Melanocortin Receptor activity. Involved in positive regulation of feeding behavior. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in familial melanoma; major depressive disorder; melanoma; oculocutaneous albinism type II; and pigmentation disease. Orthologous to human MC1R (melanocortin 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]