2. Gene
  3. NPY - Npy neuropeptide Y Gene

NPY - Npy neuropeptide Y Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: NPY02; RATNPY; RATNPY02

基因 ID: 24604 | 基因类型: protein coding

关于 NPY

功能概要

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. Studies in the rat model of depression (Flinders Sensitive Line) show that this gene is downregulated in the hippocampus and the prefrontal cortex compared to the control ((Flinders Resistant Line). Alternatively spliced transcript variants of this gene have been described, but the function of all the variants is not known. [provided by RefSeq, Jul 2012]

NPY 基因产物(1)

mRNA Protein Name
NM_012614.2 NP_036746.1 pro-neuropeptide Y preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables neuropeptide Y receptor binding IMP
IMP: 通过突变表型推断
12446577 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adult feeding behavior IDA
IDA: 通过直接分析推断
9590691 RGD
involved in chemical synaptic transmission IDA
IDA: 通过直接分析推断
12482942 RGD
involved in monocyte activation IDA
IDA: 通过直接分析推断
15342191 RGD
involved in negative regulation of acute inflammatory response to antigenic stimulus IDA
IDA: 通过直接分析推断
18805447 RGD
involved in negative regulation of blood pressure IMP
IMP: 通过突变表型推断
15699473 RGD
involved in neuropeptide signaling pathway IMP
IMP: 通过突变表型推断
15703301 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
21595512 RGD
involved in positive regulation of appetite IDA
IDA: 通过直接分析推断
9590691 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
21595512 RGD
involved in positive regulation of cell-substrate adhesion IDA
IDA: 通过直接分析推断
15342191 RGD
involved in positive regulation of dopamine metabolic process IDA
IDA: 通过直接分析推断
19579268 RGD
involved in positive regulation of eating behavior IDA
IDA: 通过直接分析推断
21303672 RGD
involved in positive regulation of nitric oxide metabolic process IDA
IDA: 通过直接分析推断
18805447 RGD
involved in regulation of nerve growth factor production IDA
IDA: 通过直接分析推断
22860197 RGD
involved in regulation of presynaptic cytosolic calcium ion concentration EXP
EXP: 通过实验结果推断
16026936 RGD
involved in regulation of presynaptic cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
16026936 RGD
involved in regulation of synaptic vesicle exocytosis EXP
EXP: 通过实验结果推断
16026936 RGD
involved in regulation of synaptic vesicle exocytosis IDA
IDA: 通过直接分析推断
16026936 RGD
involved in short-day photoperiodism IEP
IEP: 通过表达模式推断
19490367 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
9590691 RGD
is active in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
29775703 RGD
located in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
29166604 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
21344400 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
17353067 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
21344400 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pro-neuropeptide Y

pro-neuropeptide Y-like

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-14423 Velneperit Antagonist 99.21% Phase 2
HY-P10026 Nisotirostide Agonist 99.45% Phase 1
Pre-clinical Phase
生物活性分子 (66)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107725 BIBO3304 Antagonist 99.96% 否
HY-101986 BIIE-0246 Antagonist 99.10% 否
HY-P10000 Peptide YY (PYY) (3-36), Human Agonist 98.57% 否
HY-116797 MS15203 99.40% 否
HY-107726 BIBP3226 TFA Antagonist 99.25% 否
HY-P0208 [Leu31,Pro34]-Neuropeptide Y (porcine) Agonist 99.39% 否
HY-P1845 PACAP-38 (31-38), human, mouse, rat Inducer 98.99% 否
HY-107565 2-Pyridylethylamine hydrochloride Agonist 99.86% 否
HY-120619 BMS-193885 Antagonist 99.91% 否
HY-P2543 Neuropeptide Y (3-36) (human, rat) Agonist 95.44% 否
HY-P0199 Pancreatic Polypeptide, human Agonist 99.82% 否
HY-P1845A PACAP-38 (31-38), human, mouse, rat TFA Inducer 98.33% 否
HY-107733 NTNCB hydrochloride Antagonist 98.36% 否
HY-107734 L 152804 Antagonist 99.89% 否
HY-107730 NPY5RA-972 Antagonist 98.99% 否
HY-P1011 Neuropeptide Y (13-36), porcine Agonist 99.79% 否
HY-P4060A Pancreatic polypeptide TFA Agonist 99.47% 否
HY-101986A BIIE-0246 hydrochloride Antagonist ≥99.0% 否
HY-107735 CYM 9484 Antagonist 98.68% 否
HY-P1324 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide Agonist 99.25% 否
HY-P10148 N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) Agonist 98.03% 否
HY-P1322 [D-Trp34]-Neuropeptide Y Agonist 98.58% 否
HY-W141779 Boc-Cys(Npys)-OH ≥98.0% 否
HY-107728 S 25585 Antagonist 99.13% 否
HY-148179 Neuropeptide Y5 receptor ligand-1 Antagonist ≥98.0% 否
HY-P3678 Neuropeptide Y (18-36) (porcine) Antagonist 98.76% 否
HY-156922 NPY-5 receptor antagonist-1 Antagonist 99.86% 否
HY-RS09511 NPY1R Human Pre-designed siRNA Set A / 否
HY-107726A BIBP3226 Antagonist / 否
HY-101986C BIIE-0246 dihydrochloride Antagonist / 否
HY-103247 EMD 66684 Antagonist / 否
HY-107723A CGP71683 Antagonist / 否
HY-107725A BIBO3304 diTFA Inhibitor / 否
HY-110107 GW438014A Antagonist 99.98% 否
HY-118198 NPY Y2 antagonist 1 Antagonist / 否
HY-120096 BIBO3304 free base Antagonist / 否
HY-P0198B [D-Arg25]-Neuropeptide Y (human) Agonist / 否
HY-P10291 [Pro34]Neuropeptide Y, porcine Agonist / 否
HY-P10545 [D-His26]-Neuropeptide Y, human, rat Agonist / 否
HY-P11291 NNC0165-1273 / 否
HY-P1322A [D-Trp34]-Neuropeptide Y TFA Agonist / 否
HY-P1324A [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA Agonist / 否
HY-P1327 BVD 10 Antagonist / 否
HY-P1817 PACAP-38 (16-38), human, mouse, rat / 否
HY-P3676 Neuropeptide Y (3-36) (porcine) Agonist / 否
HY-P3679 Neuropeptide Y (1-24) (human) Activator / 否
HY-P4101 Cys(Npys)-TAT (47-57) / 否
HY-P4123 TAT (47-57) GGG-Cys(Npys) / 否
HY-P5757 (D-Trp32)-Neuropeptide Y (porcine) Agonist / 否
HY-RS09510 NPY Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09512 Npy1r Mouse Pre-designed siRNA Set A / 否
HY-RS09513 Npy1r Rat Pre-designed siRNA Set A / 否
HY-RS09514 NPY2R Human Pre-designed siRNA Set A / 否
HY-RS09515 Npy2r Mouse Pre-designed siRNA Set A / 否
HY-RS09516 NPY2R Rat Pre-designed siRNA Set A / 否
HY-RS09517 NPY4R Human Pre-designed siRNA Set A / 否
HY-RS09518 Npy4r Mouse Pre-designed siRNA Set A / 否
HY-RS09519 Npy4r Rat Pre-designed siRNA Set A / 否
HY-RS09520 NPY5R Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09521 Npy5r Mouse Pre-designed siRNA Set A / 否
HY-RS09522 Npy5r Rat Pre-designed siRNA Set A / 否
HY-RS16546 Npy Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22978 Npy Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W336281 Fmoc-Cys(npys)-OH / 否
HY-P1532 Pancreatic Polypeptide, rat Agonist / 否
HY-P1537 Pancreatic Polypeptide, bovine Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens NPY NCBI NCBI:4852
Mus musculus NPY NCBI NCBI:109648
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