2. Gene
  3. Spr - sepiapterin reductase Gene

Spr - sepiapterin reductase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29270 | 基因类型: protein coding

关于 Spr

功能概要

Enables sepiapterin reductase activity. Involved in response to organic substance and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in dystonia and sepiapterin reductase deficiency. Orthologous to human SPR (sepiapterin reductase). [provided by Alliance of Genome Resources, Apr 2022]

Spr 基因产物(1)

mRNA Protein Name
NM_019181.1 NP_062054.1 sepiapterin reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sepiapterin reductase (NADP+) activity IDA
IDA: 通过直接分析推断
2179471 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
12604243 RGD
involved in tetrahydrobiopterin biosynthetic process IMP
IMP: 通过突变表型推断
2179471 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sepiapterin reductase

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9905 Cetuximab Inhibitor 99.70% 否
Clinical Phase
生物活性分子 (10)
目录号 产品名 作用方式
纯度 Phase
HY-101533 AZD-5991 Inhibitor 99.79% Phase 2
HY-113603 Tildacerfont Inhibitor 98.25% Phase 2
HY-135655 Fobrepodacin disodium Inhibitor 99.53% Phase 2
HY-135655A Fobrepodacin Inhibitor / Phase 2
HY-P1649B SPR741 acetate Inhibitor 99.44% Phase 1
HY-128780B SPR206 acetate Inhibitor 98.88% Phase 1
HY-P1649 SPR741 Inhibitor 99.08% Phase 1
HY-101533B AZD-5991 (S-enantiomer) Inhibitor 99.83% Phase 1
HY-128780 Upleganan Inhibitor / Phase 1
HY-P1649A SPR741 TFA Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (36)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13963 ZCL278 Inhibitor 98.49% 否
HY-115510 SPR inhibitor 3 Inhibitor 99.84% 否
HY-122611A CSRM617 hydrochloride 99.97% 否
HY-114388 QM385 Inducer 99.48% 否
HY-135691 hnRNPK-IN-1 ≥97.0% 否
HY-160477 DC-SX029 Inhibitor 98.07% 否
HY-12930 SPR719 Inhibitor 99.39% 否
HY-101964 SPI-112 Inhibitor 98.01% 否
HY-Y1049 2-Amino-6-bromopyridine Inhibitor 99.97% 否
HY-P3143 BMSpep-57 Inhibitor 99.84% 否
HY-101931 hVEGF-IN-1 Inhibitor 99.26% 否
HY-162960 pan-KRAS degrader 1 Degrader 99.93% 否
HY-P3143A BMSpep-57 hydrochloride Inhibitor 99.69% 否
HY-159652 KRAS inhibitor-31 Inhibitor 99.36% 否
HY-116992 Chloroneb Inhibitor ≥95.0% 否
HY-113603S Tildacerfont-d8 / 否
HY-122611 CSRM617 / 否
HY-150506 SPR7 Inhibitor / 否
HY-152220 SPR39 Inhibitor / 否
HY-152222 SPR38 Inhibitor / 否
HY-152224 SPR41 Inhibitor / 否
HY-160481 MG-1102 Inhibitor / 否
HY-161841 Antitumor agent-177 Inhibitor / 否
HY-168536 SJ46411 / 否
HY-168847 INCB159020 Inhibitor / 否
HY-169311 KRAS inhibitor-37 Inhibitor / 否
HY-172196 LH168 / 否
HY-174301 USP7-IN-18 / 否
HY-176732 MJ-26 Inhibitor / 否
HY-P3852 Neurokinin Receptor (393-407), rat / 否
HY-RS13708 SPR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14143 TACR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14144 Tacr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-168535 SJ6145 / 否
HY-RS16730 Spr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23166 Spr Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P9S0008 Cetuximab (PBS) Inhibitor 99.23% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spr NCBI NCBI:6697
Mus musculus Spr NCBI NCBI:20751
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