2. Gene
  3. Spr - sepiapterin reductase Gene

Spr - sepiapterin reductase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm10328

基因 ID: 20751 | 基因类型: protein coding

关于 Spr

功能概要

Enables protein homodimerization activity. Acts upstream of or within several processes, including Catecholamine metabolic process; serotonin metabolic process; and voluntary musculoskeletal movement. Located in mitochondrion. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and skeleton. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in dystonia and sepiapterin reductase deficiency. Orthologous to human SPR (sepiapterin reductase). [provided by Alliance of Genome Resources, Apr 2022]

Spr 基因产物(1)

mRNA Protein Name
NM_011467.2 NP_035597.2 sepiapterin reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
9405351 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within L-phenylalanine metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within cell morphogenesis involved in neuron differentiation IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within dopamine metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within norepinephrine metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within pteridine metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within serotonin metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within tetrahydrobiopterin metabolic process IMP
IMP: 通过突变表型推断
16532389 MGI
acts upstream of or within voluntary musculoskeletal movement IMP
IMP: 通过突变表型推断
16532389 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sepiapterin reductase

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9905 Cetuximab Inhibitor 99.70% 否
Clinical Phase
生物活性分子 (10)
目录号 产品名 作用方式
纯度 Phase
HY-101533 AZD-5991 Inhibitor 99.79% Phase 2
HY-135655 Fobrepodacin disodium Inhibitor 99.53% Phase 2
HY-113603 Tildacerfont Inhibitor 98.25% Phase 2
HY-135655A Fobrepodacin Inhibitor / Phase 2
HY-128780B SPR206 acetate Inhibitor 98.88% Phase 1
HY-P1649B SPR741 acetate Inhibitor 99.44% Phase 1
HY-P1649 SPR741 Inhibitor 99.08% Phase 1
HY-101533B AZD-5991 (S-enantiomer) Inhibitor 99.83% Phase 1
HY-128780 Upleganan Inhibitor / Phase 1
HY-P1649A SPR741 TFA Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (40)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13963 ZCL278 Inhibitor 98.49% 否
HY-115510 SPR inhibitor 3 Inhibitor 99.01% 否
HY-122611A CSRM617 hydrochloride 99.97% 否
HY-114388 QM385 Inducer 99.48% 否
HY-135691 hnRNPK-IN-1 97.0% 否
HY-160477 DC-SX029 Inhibitor 98.07% 否
HY-12930 SPR719 Inhibitor 99.39% 否
HY-101964 SPI-112 Inhibitor 98.01% 否
HY-P3143 BMSpep-57 Inhibitor 99.84% 否
HY-Y1049 2-Amino-6-bromopyridine Inhibitor 99.97% 否
HY-159652 KRAS inhibitor-31 Inhibitor 99.36% 否
HY-162960 pan-KRAS degrader 1 Degrader 99.93% 否
HY-101931 hVEGF-IN-1 Inhibitor 99.26% 否
HY-113603S Tildacerfont-d8 / 否
HY-175207 CHI3L1-IN-3 Inhibitor 98.95% 否
HY-P3143A BMSpep-57 hydrochloride Inhibitor 99.69% 否
HY-116992 Chloroneb Inhibitor ≥95.0% 否
HY-122611 CSRM617 / 否
HY-13963S ZCL278-13C / 否
HY-150506 SPR7 Inhibitor / 否
HY-152220 SPR39 Inhibitor / 否
HY-152222 SPR38 Inhibitor / 否
HY-152224 SPR41 Inhibitor / 否
HY-160481 MG-1102 Inhibitor / 否
HY-161841 Antitumor agent-177 Inhibitor / 否
HY-168536 SJ46411 / 否
HY-168847 INCB159020 Inhibitor / 否
HY-169311 KRAS inhibitor-37 Inhibitor / 否
HY-172196 LH168 / 否
HY-174301 USP7-IN-18 / 否
HY-176537 RGN6024 / 否
HY-176732 MJ-26 Inhibitor / 否
HY-177512 MSC778 Inhibitor / 否
HY-P3852 Neurokinin Receptor (393-407), rat / 否
HY-RS13708 SPR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14143 TACR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14144 Tacr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-168535 SJ6145 / 否
HY-RS16730 Spr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23166 Spr Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P9S0008 Cetuximab (PBS) Inhibitor 99.23% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spr NCBI NCBI:6697
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