2. Gene
  3. Lrp6 - LDL receptor related protein 6 Gene

Lrp6 - LDL receptor related protein 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 312781 | 基因类型: protein coding

关于 Lrp6

功能概要

Predicted to enable several functions, including Wnt-protein binding activity; Frizzled binding activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including canonical Wnt signaling pathway; positive regulation of cytosolic calcium ion concentration; and response to peptide hormone. Located in neuronal cell body and synapse. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human LRP6 (LDL receptor related protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Lrp6 基因产物(2)

mRNA Protein Name
NM_001107892.1 NP_001101362.1 low-density lipoprotein receptor-related protein 6
NM_001401820.1 NP_001388749.1 low-density lipoprotein receptor-related protein 6 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
18006602 RGD
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
18006602 RGD
involved in chemical synaptic transmission IMP
IMP: 通过突变表型推断
20404321 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
20404321 RGD
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
18006602 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
15962290 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
20404321 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low-density lipoprotein receptor-related protein 6

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-17439 Salinomycin sodium salt 99.81% 是
HY-15597 Salinomycin 99.74% 是
HY-122816 HLY78 98.44% 否
HY-D0961 Gallocyanine chloride Activator 92.00% 否
HY-100853 IWP-O1 Inhibitor 99.81% 否
HY-RS16293 Lrp6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-160709 Wnt/β-catenin-IN-2 Inhibitor 99.46% 否
HY-176488 Y-99 Inhibitor / 否
HY-E70390 C1s Enzyme Antagonist / 否
HY-E70661 CDK14/CycY Recombinant Human Active Protein Kinase / 否
HY-RS07801 LRP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23672 Lrp6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991311 GSK3178022 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrp6 NCBI NCBI:4040
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