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  4. Glycolate oxidase-IN-1

Glycolate oxidase-IN-1(compound 26)，水杨酸衍生物，是一种乙醇酸氧化酶 (GO) 抑制剂，其 IC50 值为 38.2 μM。Glycolate oxidase-IN-1 具有降低高草酸肝细胞中草酸盐生成的能力，可用于原发性高草酸尿症 1 型 (PH1) 研究。

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Glycolate oxidase-IN-1 Chemical Structure

Glycolate oxidase-IN-1 Chemical Structure

CAS No. : 330977-65-6

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Glycolate oxidase-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1)[1].

体外研究
(In Vitro)

Glycolate oxidase-IN-1(compound 26)(0-12.5 μM, 48 h)处理小鼠肝细胞，在浓度为 6.25 μM 时，排出的草酸盐水平显着降低 67.3 ± 32%。在 12.5 μM 的浓度下，处理 24 小时和 48 小时后分别减少105.8 ± 29.2% 和 62.3 ± 24.4%，且没有任何细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Glycolate oxidase-IN-1 相关抗体:
分子量

232.19

Formula

C12H8O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Glycolate oxidase-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Glycolate oxidase-IN-1330977-65-6Otherssalicylic acid derivativeglycolate oxidasehyperoxalate hepatocyteshyperoxaluriaInhibitorinhibitorinhibit

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