1. Apoptosis
  2. c-Myc Apoptosis
  3. GQC-05

GQC-05 (NSC338258),Ellipticine (HY-15753) 衍生物,是一种强效且具有选择性的 c-Myc G-四链体 ( c-Myc G4) 稳定剂,其 KD 值为 0.1-1.43 μM。GQC-05 能够降低 Myc 的表达并诱导癌细胞凋亡 (apoptosis)。GQC-05 可用于癌症研究,如伯基特淋巴瘤。

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GQC-05

GQC-05 Chemical Structure

CAS No. : 501662-77-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GQC-05 (NSC338258), Ellipticine (HY-15753) derivative, is potent and selective c-Myc G-quadruplex ( c-Myc G4) stabilizer with KD values of 0.1-1.43 μM. GQC-05 can reduce Myc expression and induce cancer cells apoptosis. GQC-05 can be used for the research of cancer, such as Burkitt lymphoma[1].

分子量

333.43

Formula

C21H23N3O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GQC-05
目录号:
HY-177872
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