2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. GR-4991W93

GR-4991W93 是一种口服有效的 5HT1B/1D Receptors 部分激动剂，对 5HT1B 和 5HT1D 的 pIC50 值分别为 6.95 和 7.80。GR-4991W93 在豚鼠体内能有效抑制电刺激诱发的血浆渗出。GR-4991W93 可用于偏头痛的相关研究。

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GR-4991W93

GR-4991W93 Chemical Structure

CAS No. : 171549-56-7

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GR-4991W93 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GR-4991W93 is an orally active partial agonist against 5HT1B/1D Receptors, with pIC50 values of 6.95 and 7.80 against 5HT1B and 5HT1D, respectively. GR-4991W93 demonstrates potent inhibition of electrically evoked plasma extravasation in the guinea pig. GR-4991W93 can be used for migraine research[1].

IC50 & Target[1]

5-HT1B Receptor

6.95 (pIC50)

5-HT1D Receptor

7.80 (pIC50)

分子量

313.39

Formula

C18H23N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GR-4991W93 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR-4991W93171549-56-75-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5HT1B/1Delectrically evoked plasma extravasationmigraineguinea pigInhibitorinhibitorinhibit

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产品名称：
GR-4991W93
目录号：
HY-19252
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