2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. GSK-2793660 free base

GSK-2793660 (free base) 是一种口服，不可逆的组织蛋白酶 C (Cathepsin C；CTSC) 抑制剂。GSK-2793660 (free base) 可用于支气管扩张的研究。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 GSK-2793660 通常具有更好的水溶性和稳定性。

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GSK-2793660 free base

GSK-2793660 free base Chemical Structure

CAS No. : 1613458-70-0

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GSK-2793660 free base 的其他形式现货产品:

Customer Review

Other Forms of GSK-2793660 free base:

GSK-2793660 free base 相关抗体

Top Publications Citing Use of Products

查看 Cathepsin 亚型特异性产品:

查看所有亚型
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GSK-2793660 (free base) is an oral, irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 (free base) can be used for the research of bronchiectasis[1][2].

IC50 & Target

Cathepsin C

 

体内研究
(In Vivo)

GSK-2793660 (free base) is a cathepsin C (also known as dipeptidyl peptidase I enzyme) inhibitor for the reaearch of cystic fibrosis, non-cystic fibrosis bronchiectasis, anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis and bronchiectasis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

357.45

Formula

C20H27N3O3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GSK-2793660 free base 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK-27936601613458-70-0GSK2793660GSK 2793660CathepsinCathepsin CCTSCbronchiectasiscysticfibrosisnon-cysticvasculitisInhibitorinhibitorinhibit

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