1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. GYKI 12743

GYKI 12743 是一种血管选择性的突触后 α-adrenoceptor 阻断剂。GYKI 12743 抑制但不能完全消除大鼠因电刺激切断的隐神经外周端引起的皮肤微循环血流减少。GYKI 12743 可用于神经系统疾病研究。

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GYKI 12743

GYKI 12743 Chemical Structure

CAS No. : 110714-10-8

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生物活性

GYKI 12743 is a vasoselective, postsynaptic α-adrenoceptor blocker. GYKI 12743 inhibits but does not completely eliminate the cutaneous microcirculatory blood flow reduction evoked by electrical stimulation of the peripheral stump of the cut saphenous nerve in rats. GYKI 12743 can be used for the study of neurological diseases[1].

分子量

337.80

Formula

C16H20ClN3O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GYKI 12743
目录号:
HY-106390A
需求量: