2. Anti-infection
  3. HIV
  4. HIV-1 inhibitor-31

HIV-1 inhibitor-31 (compound 4) 是一种有效的 HIV-1 抑制剂。HIV-1 inhibitor-31 可用于艾滋病的研究。

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HIV-1 inhibitor-31

HIV-1 inhibitor-31 Chemical Structure

CAS No. : 920036-04-0

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HIV-1 inhibitor-31 相关抗体

Top Publications Citing Use of Products

查看 HIV 亚型特异性产品:

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HIV-1 inhibitor-31 (compound 4) is a potent HIV-1 inhibitor. HIV-1 inhibitor-31 can be used for researching AIDS[1].

IC50 & Target

HIV-1[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MT4 IC50
13.8 nM
Compound: 22
Antiviral activity against HIV1 with RT Y181C mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT Y181C mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
141 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N/Y181C mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N/Y181C mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
171 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N/Y181C/G190A mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N/Y181C/G190A mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
2.6 nM
Compound: 22
Antiviral activity against HIV1 with RT L100I mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT L100I mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
20.3 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N/V179E mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N/V179E mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
21 nM
Compound: 22
Antiviral activity against HIV1 with RT K101E/G190A mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K101E/G190A mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
21.7 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N/G190A mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N/G190A mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
23.4 nM
Compound: 22
Antiviral activity against HIV1 with RT G190S mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT G190S mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
29.3 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N/P225H mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N/P225H mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
35.8 nM
Compound: 22
Antiviral activity against HIV1 with RT Y181C/G190A mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT Y181C/G190A mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
4.7 nM
Compound: 22
Antiviral activity against HIV1 in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
7.9 nM
Compound: 22
Antiviral activity against HIV1 with RT K103N mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT K103N mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
9.4 nM
Compound: 22
Antiviral activity against HIV1 with RT G190A mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT G190A mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
MT4 IC50
> 1000 nM
Compound: 22
Antiviral activity against HIV1 with RT Y188L mutation in human MT4 cells in presence of 40% normal human serum
Antiviral activity against HIV1 with RT Y188L mutation in human MT4 cells in presence of 40% normal human serum
[PMID: 18396399]
分子量

410.25

Formula

C21H13Cl2N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HIV-1 inhibitor-31 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1 inhibitor-31920036-04-0HIVHuman immunodeficiency virusAIDSAnti-HIVInhibitorinhibitorinhibit

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产品名称：
HIV-1 inhibitor-31
目录号：
HY-146088
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