2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage Anti-infection
  3. HSP Influenza Virus
  4. HSP90-IN-14

HSP90-IN-14 (compound 4) 是一种有效的 Hsp90 (热休克蛋白 90) 抑制剂，其 Kd 为 0.26 μM。HSP90-IN-14 在 MDCK 细胞中表现出抗流感病毒活性，对 A/H3N2、A/H1N1 和 B 型流感病毒的 EC50 值分别为 2.6、3.9 和 17 μM.

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HSP90-IN-14 Chemical Structure

HSP90-IN-14 Chemical Structure

CAS No. : 1995132-67-6

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HSP90-IN-14 相关抗体

Top Publications Citing Use of Products

查看 HSP 亚型特异性产品:

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HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1].

IC50 & Target

HSP90β

0.26 ± 0.0 μM (Kd)

体外研究
(In Vitro)

HSP90-IN-14 (compound 4) (50 µM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HSP90-IN-14 相关抗体:
分子量

399.21

Formula

C14H8Cl2N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HSP90-IN-14 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HSP90-IN-141995132-67-6HSPInfluenza VirusHeat shock proteinsMDCK cellsanti-influenza virus activityantiviral agentBenzo[d]thiazoleHsp90influenza virusInhibitorinhibitorinhibit

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