2. Anti-infection
  3. HSV
  4. LANA

LANA 是一种卡波西肉瘤疱疹病毒 (KSHV) 的潜伏相关核抗原。LANA 的核心功能是作为病毒基因组的“锚”，将其拴系在宿主细胞的染色质上。LANA 确保 KSHV 的附加体 DNA 与宿主染色体一起复制并平均分配到子细胞中，从而在细胞群体中维持病毒的潜伏感染。LANA 能调控病毒和宿主细胞的基因转录，并调控某些宿主细胞基因以促进细胞存活。LANA 可用于研究病毒 DNA 拴系结构。

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LANA

LANA Chemical Structure

CAS No. : 878495-58-0

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LANA 相关抗体

Top Publications Citing Use of Products

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HSV-1 HSV-2 HSV

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LANA is a KSHV latency-associated nuclear antigen. The core function of LANA is to act as an "anchor" for the viral genome, attaching it to the chromatin of the host cell. LANA ensures that the episomal DNA of KSHV replicates together with the host chromosome and is evenly distributed among the daughter cells, thereby maintaining the latent infection of the virus in the cell population. LANA can regulate the transcription of viral and host cell genes, and regulate certain host cell genes to promote cell survival. LANA can be used to study the viral DNA tethering structure[1].

分子量

2359.75

Formula

C95H167N35O29S3
CAS 号
Sequence

Met-Ala-Pro-Pro-Gly-Met-Arg-Leu-Arg-Ser-Gly-Arg-Ser-Thr-Gly-Ala-Pro-Leu-Thr-Arg-Gly-Ser-Cys
Sequence Shortening

MAPPGMRLRSGRSTGAPLTRGSC
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LANA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LANA878495-58-0HSVHerpes simplex virusp12 proteinviral DNA tetheringchromatin bindingMuLV Gagnuclear retentioncomplementationchimeric virusesintegration site selectionInhibitorinhibitorinhibit

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目录号：
HY-P11137
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