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  4. LJP 1586

LJP 1586 是一种胺基氨基脲敏感胺氧化酶 (SSAO) 活性抑制剂。 LJP 1586 是一种具有口服有效且选择性的啮齿动物和人类 SSAO 活性抑制剂，IC50 值在 4 至 43 nM 之间。LJP 1586 对中性粒细胞积累具有显着的剂量依赖性抑制作用。

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LJP 1586 Chemical Structure

LJP 1586 Chemical Structure

CAS No. : 955037-42-0

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规格 价格 是否有货 数量
1 mg ￥2207
1 周
5 mg   询价  
10 mg   询价  

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Customer Review

LJP 1586 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].

体内研究
(In Vivo)

LJP 1586（0-10mg/kg，口服）可完全抑制大鼠肺 SSAO，ED50 介于 0.1 至 1 mg/kg 之间，药效半衰期大于 24 小时[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

231.69

Formula

C11H15ClFNO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LJP 1586 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LJP 1586955037-42-0LJP1586LJP-1586OthersInhibitorinhibitorinhibit

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产品名称：
LJP 1586
目录号：
HY-111016
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