2. Anti-infection
  3. Beta-lactamase Bacterial
  4. LN-1-255 sodium

LN-1-255 sodium 是一种 β-内酰胺酶 (β-Lactamase) 抑制剂，LN-1-255 sodium 广谱抑制 D 类碳青霉烯酶 (CHDLs)，对 OXA-48 的 IC50 为 3 nM，对 OXA-23、OXA-24/40 等也具有强大活性。LN-1-255 sodium 与碳青霉烯类抗生素联用具有协同效应。LN-1-255 sodium 可用于研究 CHDLs 所引发的细菌耐药性危机。

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LN-1-255 sodium

LN-1-255 sodium Chemical Structure

CAS No. : 247115-03-3

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LN-1-255 sodium 相关抗体

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Metallo-β-lactamase (MBL) Serine β-lactamase (SBL)

  • 生物活性

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生物活性

LN-1-255 sodium is a β-lactamase inhibitor. LN-1-255 sodium has broad-spectrum inhibitory effect on type D carbapenemases (CHDLs) with an IC50 for OXA-48 of 3 nM, and it also has strong activity against OXA-23, OXA-24/40, etc. LN-1-255 sodium combined with carbapenem antibiotics has a synergistic effect. LN-1-255 sodium can be used to study the bacterial resistance crisis caused by CHDLs[1][2].

分子量

510.45

Formula

C22H19N2NaO9S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LN-1-255 sodium 相关分类

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Keywords:

LN-1-255247115-03-3Beta-lactamaseBacterialβ-lactamaseβ-lactamase inhibitorsAcinetobacter baumanniiantimicrobial resistancecarbapenem-hydrolyzing class D β-lactamasesInhibitorinhibitorinhibit

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