1. Antibody-drug Conjugate/ADC Related
    Cell Cycle/DNA Damage
    Cytoskeleton
  2. Drug-Linker Conjugates for ADC
    Microtubule/Tubulin
  3. MC-Alkyl-Hydrazine Modified MMAF

MC-Alkyl-Hydrazine Modified MMAF 

目录号: HY-128961
产品使用指南

MC-Alkyl-Hydrazine Modified MMAF 是抗体药物复合体的一部分 (drug-linker conjugate for ADC),具有抗癌活性,是由修饰过的 MMAF (一种微管蛋白抑制剂) 和不可分割的 MC-Alkyl-Hydrazine 连接桥连接而成。

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MC-Alkyl-Hydrazine Modified MMAF Chemical Structure

MC-Alkyl-Hydrazine Modified MMAF Chemical Structure

CAS No. : 1404071-64-2

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Description

MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine[1].

IC50 & Target[1]

Auristatin

 

Molecular Weight

1133.42

Formula

C₅₉H₉₂N₁₀O₁₂

CAS No.

1404071-64-2

SMILES

O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCC(NNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

MC-Alkyl-Hydrazine Modified MMAFDrug-Linker Conjugates for ADCMicrotubule/TubulinInhibitorinhibitorinhibit

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产品名称:
MC-Alkyl-Hydrazine Modified MMAF
目录号:
HY-128961
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